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Prof. Dr. Kenneth C. Holmes

Telefon:+49 6221 486-270Fax:+49 6221 486-437

E-Mail: holmes@​mpimf-heidelberg.mpg.de

http://www.mpimf-heidelberg.mpg.de/~holmes/

Referenzen

Klug, A.; Crowther, R. A.
Three-dimensional image reconstruction from the viewpoint of information theory
Nature 238, 435 - 440 (1972)
Gilbert, P.
Ph.D. Thesis
University of Cambridge (1972)
Crowther, R. A.; DeRosier, D. J.; Klug, A.
The reconstruction of a three-dimensional structure from projections and its application to electron microscopy
Proc. R. Soc. Lond. A 317 (1530) 319 - 340 (1970)
Diamond, R.
Filtering in the Method of Least-Squares
Acta Cryst. B 25, 805 (1969)
Holmes, K. C.; Angert, I.; Kull, F. J.; Jahn, W.; Schröder, R. R.
Electron cryo-microscopy shows how strong binding of myosin to actin releases nucleotide
Nature 425, 423 - 427 (2003)

Axial Tomography by filtered least squares

We actually start out with the back projection

HTb, the right hand side of equation 2, is a vector derived from the observations that is central feature of the least squares method. Noteworthy, in the present context, HTb assumes a special significance; it is in fact the back projection! This comes about because H is a projector matrix.

 
http://www.mpimf-heidelberg.mpg.de/emeritusgruppen/biophysik/axial_tomography?seite=3
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