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Research Groups
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Anton Meinhart Group - mRNA Processing
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RNA is the exclusive messenger that forwards genetic information for protein synthesis to the ribosome. In eucaryotic organisms, genes are transcribed into messenger RNA (mRNA) by RNA polymerase II in the nucleus. The pre mRNA resides in the nucleus and ...
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Tatiana Domratcheva Group - Computational Photobiology
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Sunlight is an important environmental factor and light-induced chemical reactions may have both beneficial and detrimental biological effects. Photon absorption produces highly reactive excited molecules which can undergo chemical changes. On the one hand, ...
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Georg Köhr Group
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Signal transduction of NMDA receptors during synaptic transmission in the hippocampus; Homeostatic and input-specific plasticity in the hippocampus; Regulation of GABA release from cerebellar interneurons.
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Ilme Schlichting Group - Heme and Flavin Enzymes
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Since light is an important environmental variable, many organisms have evolved signalling pathways that transmit and thereby translate this stimulus into various biochemical activities. Recently, new classes of blue light photoreceptors have been identified ...
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Ilme Schlichting Group - Coherent diffractive imaging
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Structural biology, and in particular scattering based techniques making use of X-rays and electrons, have provided high-resolution insight in the structure and function of molecules and molecular assemblies. Despite a lot of advances in instrumentation, the ...
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Jochen Reinstein Group - Molecular Chaperones
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Protein folding is often assisted by molecular chaperones. They not only prevent undesired side reactions but even revert already aggregated proteins into their native form. How the chemical energy of ATP is used by these molecular machines and switches to ...
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Johann Bollmann Group
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During development, the nervous system is assembled by an ever increasing number of neurons that gradually acquire their mature structure and function over the course of days, weeks and months. Despite the dynamic nature of early neuronal connections in a ...
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Rolf Sprengel Group
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One of the most fascinating problems of modern biology concerns the molecular mechanisms which underlie the acquisition, computation and storage of information in the human brain. It has been a long-standing assumption that both the number of nerve cells and ...
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Thomas Euler Group - Dendritic Processing in the Retina
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The retina is a powerful image processor: It analyzes the incoming light pattern, extracts and filters temporal, spatial and chromatic aspects of the visual scene and relays this information to higher visual centers of the brain.
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Witzemann / Koenen Group - Molecular anatomy of the neuromuscular junction
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Our long term goal is to establish the anatomy of the muscle endplate at the supramolecular level and its dependence on gene expression in order to understand inherited muscle dysfunctions, in particular channelopathies. This is done by generating mouse models ...
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Wolfgang Kabsch Group
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X-ray Detector Software for processing single-crystal monochromatic diffraction data recorded by the rotation method. For a description of the package, including references, visit xds_doc. XDS can process data images from CCD-, imaging-plate, and ...
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