Many mammalian cells are enveloped by a sugar-protein coat. This coat plays a maior role in all interactions of the cell with its environment. Thus our main research interest is the analysis of the dynamic properties of this pericellular matrix.
The goal of the group is to determine how nanoscale features of the extracellular environment control cell function. We focus on the spatial regulation of integrin receptor clustering and on the cross talk with other transmembrane receptors.