Publikationen

Becker, A.; Schlichting, I.; Kabsch, W.; Groche, D.; Schultz, S.; Wagner, A. F. V.: Iron center, substrate recognition and mechanism of peptide deformylase. Nature Structural and Molecular Biology 5 (12), S. 1053 - 1058 (1998)

Lavie, A.; Ostermann, N.; Brundiers, R.; Goody, R. S.; Reinstein, J.; Konrad, M.; Schlichting, I.: Structural basis for efficient phosphorylation of 3'-azidothymidine monophosphate by Escherichia coli thymidylate kinase. Proceedings of the National Academy of Sciences of the United States of America 95 (24), S. 14045 - 14050 (1998)

Hasson, M. S.; Schlichting, I.; Moulai, J.; Taylor, K.; Barrett, W.; Kenyon, G. L.; Babbitt, P. C.; Gerlt, J. A.; Petsko, G. A.; Ringe, D.: Evolution of an enzyme active site − the structure of a new crystal form of muconate lactonizing enzyme compared with mandelate racemase and enolase. Proceedings of the National Academy of Sciences of the United States of America 95 (18), S. 10396 - 10401 (1998)

Groche, D.; Becker, A.; Schlichting, I.; Kabsch, W.; Schultz, S.; Wagner, A. F. V.: Isolation and crystallization of functionally competent Escherichia coli peptide deformylase forms containing either iron or nickel in the active site. Biochemical and Biophysical Research Communications 246 (2), S. 342 - 346 (1998)

Becker, A.; Schlichting, I.; Kabsch, W.; Schultz, S.; Wagner, A. F. V.: Structure of peptide deformylase and identification of the substrate binding site. The Journal of Biological Chemistry 273 (19), S. 11413 - 11416 (1998)

Schneider, T. R.; Gerhardt, E.; Lee, M.; Liang, P.; Anderson, K. S.; Schlichting, I.: Loop closure and intersubunit communication in tryptophan synthase. Biochemistry 37 (16), S. 5394 - 5406 (1998)

Lavie, A.; Konrad, M.; Brundiers, R.; Goody, R. S.; Schlichting, I.; Reinstein, J.: Crystal structure of yeast thymidylate kinase complexed with the bisubstrate inhibitor P1-(5'-adenosyl) P5-(5'-thymidyl) pentaphosphate (TP5A) at 2.0 A resolution: implications for catalysis and AZT activation. Biochemistry 37 (11), S. 3677 - 3686 (1998)

Lavie, A.; Reinstein, J.; Goody, R. S.; Schlichting, I.; Konrad, M.: Improving AZT efficacy. Nature Medicine 4 (2), S. 132 - 132 (1998)

Lavie, A.; Reinstein, J.; Goody, R. S.; Schlichting, I.; Konrad, M.: Reply to "Improving AZT efficacy". Nature Medicine 4, S. 132 - 132 (1998)